Regulation of Hematopoiesis by Chemokine Family Members

Overview

Journal Int J Hematol

Specialty Hematology

Date 2001 Sep 4

PMID 11530812

Citations 25

Authors

H E Broxmeyer

Affiliations

Soon will be listed here.

Abstract

Chemokines, originally designated as chemoattractant cytokines, comprise a large family of molecules that have been implicated in a number of different functions mediated through chemokine receptors. Among these functions are regulatory roles in hematopoiesis that encompass effects on the proliferation, survival, and homing/migration of myeloid progenitor cells. This article reviews the field of chemokine regulation of hematopoiesis at the level of myeloid progenitor cells.

Citing Articles

DEK, a nuclear protein, is chemotactic for hematopoietic stem/progenitor cells acting through CXCR2 and Gαi signaling.

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CXCL15/Lungkine has suppressive activity on proliferation and expansion of multi-potential, erythroid, granulocyte and macrophage progenitors in S-phase specific manner.

Broxmeyer H, Cooper S, Ropa J Blood Cells Mol Dis. 2021; 91:102594.

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Fibronectin and Its Receptors in Hematopoiesis.

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Myelopoiesis of the Amphibian Is Segregated to the Bone Marrow, Away From Their Hematopoietic Peripheral Liver.

Yaparla A, Reeves P, Grayfer L Front Immunol. 2020; 10:3015.

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Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling.

Capitano M, Mor-Vaknin N, Saha A, Cooper S, Legendre M, Guo H J Clin Invest. 2019; 129(6):2555-2570.

PMID: 31107242 PMC: 6546479. DOI: 10.1172/JCI127460.

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