» Articles » PMID: 1152352

[Carcinofetal Antigens. III. Further Carcinofetal Antigens (author's Transl)]

Overview
Journal Klin Wochenschr
Specialty General Medicine
Date 1975 May 1
PMID 1152352
Authors
Affiliations
Soon will be listed here.
Abstract

The occurrance and significance of important carcinofetal antigens other than AFP and CEA are reported. These included the alpha 2 H-protein which is produced in the liver and increases in serum of patients with various tumors, the fetal sulphoglycoprotein antigen FSA from the gastric juice of patients with gastric cancer, the carcinoplacental alkaline phosphatase (REGAN-isoenzyme)which is found in the serum of patients suffering from e.g. bronchogenic, mammary, urogenital and gastrointestinal carcinomas, the beta-S-fetoprotein which is most likely to be identical with C-reactive protein, gamma-fetoprotein, the carcinofetal antigen in glial tumors (CFGA); ectopic production of placental hormones like human gonadotropin, placental lactogen, plasminogen-activators; leukemia-associated antigens. Furthermore, some other less known carcinofetal antigens are mentioned.

References
1.
Primus F, Wang R, Goldenberg D, Hansen H . Localization of human GW-39 tumors in hamsters by radiolabeled heterospecific antibody to carcinoembryonic antigen. Cancer Res. 1973; 33(11):2977-82. View

2.
Inglis N, Guzek D, Kirley S, Green S, FISHMAN W . Rapid electrophoretic microzone membrane technique for Regan isoenzyme (placental type alkaline phosphatase) usine a fluorogenic substrate. Clin Chim Acta. 1971; 33(2):287-92. DOI: 10.1016/0009-8981(71)90485-2. View

3.
Bali J, Fournajoux J, Sebah H, BALMES , MARIGNAN R . [Comparative study of 2 direct methods for the radioimmunologic determination of carcinoembryonic antigen]. Biol Gastroenterol (Paris). 1973; 6(4):297-306. View

4.
Freedman S . Carcinoembryonic antigen: current clinical applications. J Allergy Clin Immunol. 1972; 50(6):348-57. DOI: 10.1016/0091-6749(72)90038-3. View

5.
Orjasaeter H, LIAVAG I, Fredriksen G . [Carcinoembryonic antigens (CES) in malignant tumors of the colon and rectum]. Tidsskr Nor Laegeforen. 1972; 92(7):497-501. View