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A Sensitivity Analysis for Publication Bias in Systematic Reviews

Overview
Publisher Sage Publications
Specialties Public Health
Science
Date 2001 Aug 9
PMID 11491412
Citations 67
Authors
Affiliations
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Abstract

There is no simple method of correcting for publication bias in systematic reviews. We suggest a sensitivity analysis in which different patterns of selection bias can be tested against the fit to the funnel plot. Publication bias leads to lower values, and greater uncertainty, in treatment effect estimates. Two examples are discussed. An appendix lists the S-plus code needed for carrying out the analysis.

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