Identification of a New Imprinted Gene, Rian, on Mouse Chromosome 12 by Fluorescent Differential Display Screening

Overview

Journal J Biochem

Publisher Oxford University Press

Specialty Biochemistry

Date 2001 Aug 2

PMID 11481034

Citations 32

Authors

I Hatada

S Morita

Y Obata

Y Sotomaru

M Shimoda

T Kono

Affiliations

Soon will be listed here.

Abstract

Systematic screening of differentially expressed genes among androgenetic, parthenogenetic, and normal embryos by means of fluorescent differential display revealed five imprinted genes. One of them, named Rian, was expressed exclusively from the maternal allele and was closely linked to an imprinted gene, Meg3(Gtl2), mapped to the distal end of chromosome 12. The Rian transcript did not have any apparent open reading frame, and its transcript was exclusively localized to the nucleus.

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