Linezolid Resistance in a Clinical Isolate of Staphylococcus Aureus

Overview

Journal Lancet

Publisher Elsevier

Specialty General Medicine

Date 2001 Jul 31

PMID 11476839

Citations 246

Authors

S Tsiodras

H S Gold

G Sakoulas

G M Eliopoulos

C WENNERSTEN

L Venkataraman

R C Moellering

M J Ferraro

Affiliations

Soon will be listed here.

Abstract

The new oxazolidinone antimicrobial, linezolid, has been approved for the treatment of infections caused by various gram-positive bacteria, including meticillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Although instances of linezolid resistance in VRE have been reported, resistance has not been encountered among clinical isolates of S aureus. We have characterised an MRSA isolate resistant to linezolid that was recovered from a patient treated with this agent for dialysis-associated peritonitis.

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