» Articles » PMID: 11470609

Polymers in Drug Delivery

Overview
Publisher Elsevier
Specialty Biochemistry
Date 2001 Jul 27
PMID 11470609
Citations 100
Authors
Affiliations
Soon will be listed here.
Abstract

Advances in polymer science have led to the development of several novel drug-delivery systems. A proper consideration of surface and bulk properties can aid in the designing of polymers for various drug-delivery applications. Biodegradable polymers find widespread use in drug delivery as they can be degraded to non-toxic monomers inside the body. Novel supramolecular structures based on polyethylene oxide copolymers and dendrimers are being intensively researched for delivery of genes and macromolecules. Hydrogels that can respond to a variety of physical, chemical and biological stimuli hold enormous potential for design of closed-loop drug-delivery systems. Design and synthesis of novel combinations of polymers will expand the scope of new drug-delivery systems in the future.

Citing Articles

Formulation, Characterisation, and Biocompatibility Assessment of Rifampicin-Loaded Poly(d,l-lactide-co-glycolide) Composites for Local Treatment of Orthopaedic and Wound Infections.

Singhal M, Seaton C, Surtees A, Katsikogianni M Pharmaceutics. 2024; 16(11).

PMID: 39598590 PMC: 11597898. DOI: 10.3390/pharmaceutics16111467.


Nanomedicines as a cutting-edge solution to combat antimicrobial resistance.

Solanki R, Makwana N, Kumar R, Joshi M, Patel A, Bhatia D RSC Adv. 2024; 14(45):33568-33586.

PMID: 39439838 PMC: 11495475. DOI: 10.1039/d4ra06117a.


Triblock copolymer micelles enhance solubility, permeability and activity of a quorum sensing inhibitor against biofilms.

Kasza K, Soukarieh F, Romero M, Hardie K, Gurnani P, Camara M RSC Appl Polym. 2024; 2(3):444-455.

PMID: 38800514 PMC: 11114570. DOI: 10.1039/d3lp00208j.


Preclinical evaluation of novel synthesised nanoparticles based on tyrosine poly(ester amide) for improved targeted pulmonary delivery.

Dahmash E, Achkar N, Ali D, Jarrar Q, Iyire A, Assaf S Sci Rep. 2024; 14(1):9845.

PMID: 38684750 PMC: 11058873. DOI: 10.1038/s41598-024-59588-1.


The Effect of Stereocomplexation and Crystallinity on the Degradation of Polylactide Nanoparticles.

Yin C, Hemstedt J, Scheuer K, Struczynska M, Weber C, Schubert U Nanomaterials (Basel). 2024; 14(5).

PMID: 38470771 PMC: 10934930. DOI: 10.3390/nano14050440.