A Four-step Synthesis of the Hydroazulene Core of Guanacastepene

Overview

Journal Org Lett

Publisher American Chemical Society

Specialties Biochemistry
Chemistry

Date 2001 Jul 21

PMID 11463326

Citations 8

Authors

G B Dudley

S J Danishefsky

Affiliations

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Abstract

[reaction: see text] A concise, four-step conversion of 2-methylcyclopentenone to hydroazulene 2 is described. An alternative approach that led to an unexpected [5,5]-bicyclic carbon framework is also discussed.

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