Tc8, a Tourist-like Transposon in Caenorhabditis Elegans

Overview

Journal Genetics

Publisher Oxford University Press

Specialty Genetics

Date 2001 Jul 17

PMID 11454757

Citations 7

Authors

Q H Le

K Turcotte

T Bureau

Affiliations

Soon will be listed here.

Abstract

Members of the Tourist family of miniature inverted-repeat transposable elements (MITEs) are very abundant among a wide variety of plants, are frequently found associated with normal plant genes, and thus are thought to be important players in the organization and evolution of plant genomes. In Arabidopsis, the recent discovery of a Tourist member harboring a putative transposase has shed new light on the mobility and evolution of MITEs. Here, we analyze a family of Tourist transposons endogenous to the genome of the nematode Caenorhabditis elegans (Bristol N2). One member of this large family is 7568 bp in length, harbors an ORF similar to the putative Tourist transposase from Arabidopsis, and is related to the IS5 family of bacterial insertion sequences (IS). Using database searches, we found expressed sequence tags (ESTs) similar to the putative Tourist transposases in plants, insects, and vertebrates. Taken together, our data suggest that Tourist-like and IS5-like transposons form a superfamily of potentially active elements ubiquitous to prokaryotic and eukaryotic genomes.

Citing Articles

hATpin, a family of MITE-like hAT mobile elements conserved in diverse plant species that forms highly stable secondary structures.

Moreno-Vazquez S, Ning J, Meyers B Plant Mol Biol. 2005; 58(6):869-886.

PMID: 16240179 DOI: 10.1007/s11103-005-8271-8.

A two-edged role for the transposable element Kiddo in the rice ubiquitin2 promoter.

Yang G, Lee Y, Jiang Y, Shi X, Kertbundit S, Hall T Plant Cell. 2005; 17(5):1559-68.

PMID: 15805485 PMC: 1091774. DOI: 10.1105/tpc.104.030528.

PIF- and Pong-like transposable elements: distribution, evolution and relationship with Tourist-like miniature inverted-repeat transposable elements.

Zhang X, Jiang N, Feschotte C, Wessler S Genetics. 2004; 166(2):971-86.

PMID: 15020481 PMC: 1470744. DOI: 10.1534/genetics.166.2.971.

MAK, a computational tool kit for automated MITE analysis.

Yang G, Hall T Nucleic Acids Res. 2003; 31(13):3659-65.

PMID: 12824388 PMC: 168938. DOI: 10.1093/nar/gkg531.

Continuous exchange of sequence information between dispersed Tc1 transposons in the Caenorhabditis elegans genome.

Fischer S, Wienholds E, Plasterk R Genetics. 2003; 164(1):127-34.

PMID: 12750326 PMC: 1462561. DOI: 10.1093/genetics/164.1.127.

References

Mahillon J, Chandler M . Insertion sequences. Microbiol Mol Biol Rev. 1998; 62(3):725-74. PMC: 98933. DOI: 10.1128/MMBR.62.3.725-774.1998. View

Bowen N, McDonald J . Genomic analysis of Caenorhabditis elegans reveals ancient families of retroviral-like elements. Genome Res. 1999; 9(10):924-35. DOI: 10.1101/gr.9.10.924. View

Surzycki S, Belknap W . Characterization of repetitive DNA elements in Arabidopsis. J Mol Evol. 1999; 48(6):684-91. DOI: 10.1007/pl00006512. View

Collins J, Anderson P . The Tc5 family of transposable elements in Caenorhabditis elegans. Genetics. 1994; 137(3):771-81. PMC: 1206037. DOI: 10.1093/genetics/137.3.771. View

Rezsohazy R, Hallet B, Delcour J, Mahillon J . The IS4 family of insertion sequences: evidence for a conserved transposase motif. Mol Microbiol. 1993; 9(6):1283-95. DOI: 10.1111/j.1365-2958.1993.tb01258.x. View

van Luenen H, Colloms S, Plasterk R . The mechanism of transposition of Tc3 in C. elegans. Cell. 1994; 79(2):293-301. DOI: 10.1016/0092-8674(94)90198-8. View

Britten R . Active gypsy/Ty3 retrotransposons or retroviruses in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 1995; 92(2):599-601. PMC: 42789. DOI: 10.1073/pnas.92.2.599. View

Yeadon P, Catcheside D . Guest: a 98 bp inverted repeat transposable element in Neurospora crassa. Mol Gen Genet. 1995; 247(1):105-9. DOI: 10.1007/BF00425826. View

Egilmez N, Ebert 2nd R, Shmookler Reis R . Strain evolution in Caenorhabditis elegans: transposable elements as markers of interstrain evolutionary history. J Mol Evol. 1995; 40(4):372-81. DOI: 10.1007/BF00164023. View

10.

Barnes T, Kohara Y, Coulson A, Hekimi S . Meiotic recombination, noncoding DNA and genomic organization in Caenorhabditis elegans. Genetics. 1995; 141(1):159-79. PMC: 1206715. DOI: 10.1093/genetics/141.1.159. View

11.

Oosumi T, Garlick B, Belknap W . Identification of putative nonautonomous transposable elements associated with several transposon families in Caenorhabditis elegans. J Mol Evol. 1996; 43(1):11-8. DOI: 10.1007/BF02352294. View

12.

Capy P, Vitalis R, Langin T, Higuet D, Bazin C . Relationships between transposable elements based upon the integrase-transposase domains: is there a common ancestor?. J Mol Evol. 1996; 42(3):359-68. DOI: 10.1007/BF02337546. View

13.

SanMiguel P, Tikhonov A, Jin Y, Motchoulskaia N, Zakharov D, Melake-Berhan A . Nested retrotransposons in the intergenic regions of the maize genome. Science. 1996; 274(5288):765-8. DOI: 10.1126/science.274.5288.765. View

14.

Ketting R, Haverkamp T, van Luenen H, Plasterk R . Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD. Cell. 1999; 99(2):133-41. DOI: 10.1016/s0092-8674(00)81645-1. View

15.

Surzycki S, Belknap W . Repetitive-DNA elements are similarly distributed on Caenorhabditis elegans autosomes. Proc Natl Acad Sci U S A. 2000; 97(1):245-9. PMC: 26648. DOI: 10.1073/pnas.97.1.245. View

16.

Hirochika H, Okamoto H, Kakutani T . Silencing of retrotransposons in arabidopsis and reactivation by the ddm1 mutation. Plant Cell. 2000; 12(3):357-69. PMC: 139836. DOI: 10.1105/tpc.12.3.357. View

17.

Feschotte C, Mouches C . Evidence that a family of miniature inverted-repeat transposable elements (MITEs) from the Arabidopsis thaliana genome has arisen from a pogo-like DNA transposon. Mol Biol Evol. 2000; 17(5):730-7. DOI: 10.1093/oxfordjournals.molbev.a026351. View

18.

Le Q, Wright S, Yu Z, Bureau T . Transposon diversity in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2000; 97(13):7376-81. PMC: 16553. DOI: 10.1073/pnas.97.13.7376. View

19.

Butler M, Wall S, Luehrsen K, Fox G, Hecht R . Molecular relationships between closely related strains and species of nematodes. J Mol Evol. 1981; 18(1):18-23. DOI: 10.1007/BF01733207. View

20.

GREENWALD I . lin-12, a nematode homeotic gene, is homologous to a set of mammalian proteins that includes epidermal growth factor. Cell. 1985; 43(3 Pt 2):583-90. DOI: 10.1016/0092-8674(85)90230-2. View