A Test of Amino Acid Reversibility

Overview

Journal J Mol Evol

Specialty Biochemistry

Date 2001 Jul 10

PMID 11443350

Citations 2

Authors

N G Smith

A Eyre-Walker

Affiliations

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Abstract

In studies of molecular evolution, the assumption that protein evolution is reversible has often been made, but rarely tested. Here we use a large set of orthologous murid protein coding sequences to perform a simple test of reversibility, and find no evidence to reject the assumption of reversibility in protein evolution.

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