Control of Chromosomal DNA Replication in the Early Xenopus Embryo

Overview

Journal EMBO J

Specialties Biotechnology
Molecular Biology

Date 2001 Jul 4

PMID 11432816

Citations 36

Authors

J J Blow

Affiliations

Soon will be listed here.

Citing Articles

Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair.

Parisis N, Dans P, Jbara M, Singh B, Schausi-Tiffoche D, Molina-Serrano D Nat Commun. 2023; 14(1):5104.

PMID: 37607906 PMC: 10444856. DOI: 10.1038/s41467-023-40843-4.

Approaches to Monitor Termination of DNA Replication Using Xenopus Egg Extracts.

Kavlashvili T, Dewar J Methods Mol Biol. 2022; 2444:105-123.

PMID: 35290634 DOI: 10.1007/978-1-0716-2063-2_7.

Myc and the Replicative CMG Helicase: The Creation and Destruction of Cancer: Myc Over-Activation of CMG Helicases Drives Tumorigenesis and Creates a Vulnerability in CMGs for Therapeutic Intervention.

Reed D, Alexandrow M Bioessays. 2020; 42(4):e1900218.

PMID: 32080866 PMC: 8223603. DOI: 10.1002/bies.201900218.

Cell-free transcription in egg extract.

Barrows J, Long D J Biol Chem. 2019; 294(51):19645-19654.

PMID: 31732562 PMC: 6926450. DOI: 10.1074/jbc.RA119.011350.

An oncologist׳s friend: How Xenopus contributes to cancer research.

Hardwick L, Philpott A Dev Biol. 2015; 408(2):180-7.

PMID: 25704511 PMC: 4684227. DOI: 10.1016/j.ydbio.2015.02.003.

References

Prokhorova T, J Blow J . Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity. J Biol Chem. 2000; 275(4):2491-8. PMC: 3626232. DOI: 10.1074/jbc.275.4.2491. View

Johnston L, Masai H, Sugino A . First the CDKs, now the DDKs. Trends Cell Biol. 1999; 9(7):249-52. DOI: 10.1016/s0962-8924(99)01586-x. View

Maiorano D, Moreau J, Mechali M . XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis. Nature. 2000; 404(6778):622-5. DOI: 10.1038/35007104. View

Nishitani H, Lygerou Z, Nishimoto T, Nurse P . The Cdt1 protein is required to license DNA for replication in fission yeast. Nature. 2000; 404(6778):625-8. DOI: 10.1038/35007110. View

Jares P, J Blow J . Xenopus cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading. Genes Dev. 2000; 14(12):1528-40. PMC: 316685. View

Mimura S, Masuda T, Matsui T, Takisawa H . Central role for cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extracts. Genes Cells. 2000; 5(6):439-52. DOI: 10.1046/j.1365-2443.2000.00340.x. View

Pelizon C, Madine M, Romanowski P, Laskey R . Unphosphorylatable mutants of Cdc6 disrupt its nuclear export but still support DNA replication once per cell cycle. Genes Dev. 2000; 14(19):2526-33. PMC: 316983. DOI: 10.1101/gad.176300. View

Walter J . Evidence for sequential action of cdc7 and cdk2 protein kinases during initiation of DNA replication in Xenopus egg extracts. J Biol Chem. 2000; 275(50):39773-8. DOI: 10.1074/jbc.M008107200. View

Wohlschlegel J, Dwyer B, Dhar S, Cvetic C, Walter J, Dutta A . Inhibition of eukaryotic DNA replication by geminin binding to Cdt1. Science. 2000; 290(5500):2309-12. DOI: 10.1126/science.290.5500.2309. View

10.

J Blow J, Gillespie P, Francis D, Jackson D . Replication origins in Xenopus egg extract Are 5-15 kilobases apart and are activated in clusters that fire at different times. J Cell Biol. 2001; 152(1):15-25. PMC: 2193667. DOI: 10.1083/jcb.152.1.15. View

11.

Labib K, Diffley J . Is the MCM2-7 complex the eukaryotic DNA replication fork helicase?. Curr Opin Genet Dev. 2001; 11(1):64-70. DOI: 10.1016/s0959-437x(00)00158-1. View

12.

Tada S, Li A, Maiorano D, Mechali M, J Blow J . Repression of origin assembly in metaphase depends on inhibition of RLF-B/Cdt1 by geminin. Nat Cell Biol. 2001; 3(2):107-13. PMC: 3605706. DOI: 10.1038/35055000. View

13.

Blumenthal A, Kriegstein H, Hogness D . The units of DNA replication in Drosophila melanogaster chromosomes. Cold Spring Harb Symp Quant Biol. 1974; 38:205-23. DOI: 10.1101/sqb.1974.038.01.024. View

14.

Harland R, Laskey R . Regulated replication of DNA microinjected into eggs of Xenopus laevis. Cell. 1980; 21(3):761-71. DOI: 10.1016/0092-8674(80)90439-0. View

15.

Lohka M, Masui Y . Formation in vitro of sperm pronuclei and mitotic chromosomes induced by amphibian ooplasmic components. Science. 1983; 220(4598):719-21. DOI: 10.1126/science.6601299. View

16.

J Blow J, Laskey R . Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs. Cell. 1986; 47(4):577-87. DOI: 10.1016/0092-8674(86)90622-7. View

17.

J Blow J, Laskey R . A role for the nuclear envelope in controlling DNA replication within the cell cycle. Nature. 1988; 332(6164):546-8. DOI: 10.1038/332546a0. View

18.

Murray A, Kirschner M . Cyclin synthesis drives the early embryonic cell cycle. Nature. 1989; 339(6222):275-80. DOI: 10.1038/339275a0. View

19.

Mahbubani H, Paull T, Elder J, J Blow J . DNA replication initiates at multiple sites on plasmid DNA in Xenopus egg extracts. Nucleic Acids Res. 1992; 20(7):1457-62. PMC: 312222. DOI: 10.1093/nar/20.7.1457. View

20.

Hyrien O, Mechali M . Plasmid replication in Xenopus eggs and egg extracts: a 2D gel electrophoretic analysis. Nucleic Acids Res. 1992; 20(7):1463-9. PMC: 312223. DOI: 10.1093/nar/20.7.1463. View