The Arabidopsis Serrate Gene Encodes a Zinc-finger Protein Required for Normal Shoot Development

Overview

Journal Plant Cell

Publisher Oxford University Press

Specialties Biology
Cell Biology

Date 2001 Jun 13

PMID 11402159

Citations 107

Authors

M J Prigge

D R Wagner

Affiliations

Soon will be listed here.

Abstract

Organogenesis in plants depends upon the proper regulation of many genes, but how such necessary changes in gene expression are coordinated is largely unknown. The serrate (se) mutant of Arabidopsis displays defects in the initiation and elaboration of cotyledons and post-embryonic lateral organs. Cloning the SE gene revealed that it encodes a protein with a single, C(2)H(2)-type, zinc finger related to genes in other eukaryotes. Consistent with a role in organogenesis, the SE gene is transcribed in shoot meristems and in emerging organ primordia throughout development. Expression of the SE cDNA under the control of a heterologous promoter caused both accelerated and arrested plant growth, and these phenotypes were due to overexpression and co-suppression of the SE gene, respectively. Our analysis of the se mutant and the SE gene suggests a role for the SE gene product in regulating changes in gene expression via chromatin modification. Consistent with this proposed function, a synergistic double mutant phenotype was seen for plants mutant at both the SE locus and the locus encoding the largest subunit of chromatin assembly factor I.

Citing Articles

Differential expression of microRNAs in response to infection in differentially responding genotypes of papaya ( L.) and its wild relative.

Patil B, Tripathi S Front Plant Sci. 2024; 15:1398437.

PMID: 38966149 PMC: 11222417. DOI: 10.3389/fpls.2024.1398437.

() Regulates the Initiation of Trichomes in and the Development of Fiber in Cotton.

Liu Y, Ma X, Li Y, Yang X, Cheng W Plants (Basel). 2024; 13(4).

PMID: 38498441 PMC: 10892670. DOI: 10.3390/plants13040492.

Mapping and Screening of Candidate Gene Regulating the Biomass Yield of Sorghum ( L.).

Li M, Cai Q, Liang Y, Zhao Y, Hao Y, Qin Y Int J Mol Sci. 2024; 25(2).

PMID: 38255870 PMC: 10815252. DOI: 10.3390/ijms25020796.

Capture of regulatory factors via CRISPR-dCas9 for mechanistic analysis of fine-tuned SERRATE expression in Arabidopsis.

Chen W, Wang J, Wang Z, Zhu T, Zheng Y, Hawar A Nat Plants. 2024; 10(1):86-99.

PMID: 38168608 DOI: 10.1038/s41477-023-01575-x.

MicroRNA156 conditions auxin sensitivity to enable growth plasticity in response to environmental changes in Arabidopsis.

Sang Q, Fan L, Liu T, Qiu Y, Du J, Mo B Nat Commun. 2023; 14(1):1449.

PMID: 36949101 PMC: 10033679. DOI: 10.1038/s41467-023-36774-9.

References

Baskin T, Cork A, Williamson R, Gorst J . STUNTED PLANT 1, A Gene Required for Expansion in Rapidly Elongating but Not in Dividing Cells and Mediating Root Growth Responses to Applied Cytokinin. Plant Physiol. 1995; 107(1):233-243. PMC: 161192. DOI: 10.1104/pp.107.1.233. View

Berna G, Robles P, Micol J . A mutational analysis of leaf morphogenesis in Arabidopsis thaliana. Genetics. 1999; 152(2):729-42. PMC: 1460616. DOI: 10.1093/genetics/152.2.729. View

Groot , Meicenheimer . Comparison of Leaf Plastochron Index and Allometric Analyses of Tooth Development in Arabidopsis thaliana. J Plant Growth Regul. 2000; 19(1):77-89. DOI: 10.1007/s003440000008. View

Byrne M, Barley R, Curtis M, Arroyo J, Dunham M, Hudson A . Asymmetric leaves1 mediates leaf patterning and stem cell function in Arabidopsis. Nature. 2001; 408(6815):967-71. DOI: 10.1038/35050091. View

Wilkins R, Lis J . Dynamics of potentiation and activation: GAGA factor and its role in heat shock gene regulation. Nucleic Acids Res. 1997; 25(20):3963-8. PMC: 147008. DOI: 10.1093/nar/25.20.3963. View

Waites R, Selvadurai H, Oliver I, Hudson A . The PHANTASTICA gene encodes a MYB transcription factor involved in growth and dorsoventrality of lateral organs in Antirrhinum. Cell. 1998; 93(5):779-89. DOI: 10.1016/s0092-8674(00)81439-7. View

Long D, Martin M, Sundberg E, Swinburne J, Puangsomlee P, Coupland G . The maize transposable element system Ac/Ds as a mutagen in Arabidopsis: identification of an albino mutation induced by Ds insertion. Proc Natl Acad Sci U S A. 1993; 90(21):10370-4. PMC: 47776. DOI: 10.1073/pnas.90.21.10370. View

Lynn K, Fernandez A, Aida M, Sedbrook J, Tasaka M, Masson P . The PINHEAD/ZWILLE gene acts pleiotropically in Arabidopsis development and has overlapping functions with the ARGONAUTE1 gene. Development. 1999; 126(3):469-81. DOI: 10.1242/dev.126.3.469. View

Tsiantis M, Schneeberger R, Golz J, Freeling M, Langdale J . The maize rough sheath2 gene and leaf development programs in monocot and dicot plants. Science. 1999; 284(5411):154-6. DOI: 10.1126/science.284.5411.154. View

10.

Timmermans M, Hudson A, Becraft P, Nelson T . ROUGH SHEATH2: a Myb protein that represses knox homeobox genes in maize lateral organ primordia. Science. 1999; 284(5411):151-3. DOI: 10.1126/science.284.5411.151. View

11.

Thomas J, Spillane C, Coluccio A, Hoeppner M, Grossniklaus U . Maintenance of genomic imprinting at the Arabidopsis medea locus requires zygotic DDM1 activity. Genes Dev. 1999; 13(22):2971-82. PMC: 317158. DOI: 10.1101/gad.13.22.2971. View

12.

Kerstetter R, Poethig R . The specification of leaf identity during shoot development. Annu Rev Cell Dev Biol. 1999; 14:373-98. DOI: 10.1146/annurev.cellbio.14.1.373. View

13.

Enomoto S, Berman J . Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci. Genes Dev. 1998; 12(2):219-32. PMC: 316446. DOI: 10.1101/gad.12.2.219. View

14.

Hoppe B, Horton R . Gel-loading dyes compatible with PCR. Biotechniques. 1992; 12(5):679-80. View

15.

Clough S, Bent A . Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. Plant J. 1999; 16(6):735-43. DOI: 10.1046/j.1365-313x.1998.00343.x. View

16.

Rossman T, Wang Z . Expression cloning for arsenite-resistance resulted in isolation of tumor-suppressor fau cDNA: possible involvement of the ubiquitin system in arsenic carcinogenesis. Carcinogenesis. 1999; 20(2):311-6. DOI: 10.1093/carcin/20.2.311. View

17.

Liu Z, Meyerowitz E . LEUNIG regulates AGAMOUS expression in Arabidopsis flowers. Development. 1995; 121(4):975-91. DOI: 10.1242/dev.121.4.975. View

18.

Kaya H, Shibahara K, Taoka K, Iwabuchi M, Stillman B, Araki T . FASCIATA genes for chromatin assembly factor-1 in arabidopsis maintain the cellular organization of apical meristems. Cell. 2001; 104(1):131-42. DOI: 10.1016/s0092-8674(01)00197-0. View

19.

Ohad N, Yadegari R, Margossian L, Hannon M, Michaeli D, Harada J . Mutations in FIE, a WD polycomb group gene, allow endosperm development without fertilization. Plant Cell. 1999; 11(3):407-16. PMC: 144179. DOI: 10.1105/tpc.11.3.407. View

20.

Yu L, Simon E, Trotochaud A, Clark S . POLTERGEIST functions to regulate meristem development downstream of the CLAVATA loci. Development. 2000; 127(8):1661-70. DOI: 10.1242/dev.127.8.1661. View