Spinal Interneuronal Systems: Identification, Multifunctional Character and Reconfigurations in Mammals

Overview

Journal J Physiol

Specialty Physiology

Date 2001 May 15

PMID 11351010

Citations 82

Authors

E Jankowska

Affiliations

Soon will be listed here.

Abstract

This review focuses on the flexibility of operation of spinal interneuronal networks and their multifunctional character in mammals. It concerns, in particular, two ways in which spinal interneuronal networks may be functionally reorganised, namely by modulating the synaptic actions of primary afferents by monoamines and by GABAergic presynaptic inhibition. The evidence will be reviewed for topographical and target-related differences in modulatory effects in various interneuronal networks and these will be related to differences in the intrinsic properties of different functional types of interneurones in these networks and to the role played by them.

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