Bone Healing in Children
Overview
Authors
Affiliations
Just as pediatric fractures and bones are basically similar to adult fractures and bones, pediatric bone healing is basically similar to adult bone healing. They both go through the three same phases of inflammation, reparation, and remodeling. It is those differences between pediatric and adult bone, however, that affect the differences in the healing of pediatric bone. Because pediatric bone can fail in compression, less initial stability and less callus formation is required to achieve a clinically stable or healed fracture. The greater subperiosteal hematoma and the stronger periosteum all contribute to a more rapid formation of callous strong enough to render the fracture healed more rapidly than the adult. Genes and hormones that are necessary for the initial formation of the skeleton are the same as, or at least similar in most instances, to those necessary for the healing of fractures. This osteogenic environment of the pediatric bone means that these fracture healing processes are already ongoing in the child at the time of the fracture. In the adult, these factors must be reawakened, leading to the slower healing time in the adult. Once the fracture is healed, the still-growing pediatric bone can correct any "sins" of fracture alignment or angulation leaving the bone with no signs of having ever been broken. The final result is bone that is, in the child's words, "as good as new."
Williams-Reid H, Johannesson A, Buis A Can Prosthet Orthot J. 2025; 7(2):43715.
PMID: 39990241 PMC: 11844765. DOI: 10.33137/cpoj.v7i2.43715.
Silvester L, Higo A, Kearney R, McWilliams D, Palmer S Injury. 2024; 55(10):111801.
PMID: 39128165 PMC: 11422290. DOI: 10.1016/j.injury.2024.111801.
Nyland J, Sirignano M, Richards J, Krupp R J Funct Morphol Kinesiol. 2024; 9(2).
PMID: 38804446 PMC: 11130880. DOI: 10.3390/jfmk9020080.
Shedding Light on Pediatric Fractures: Bridging the Knowledge Gap.
Van Bergen C, Colaris J Children (Basel). 2024; 11(5).
PMID: 38790560 PMC: 11120606. DOI: 10.3390/children11050565.
A novel method for evaluating mastoid defect regrowth after cochlear implantation.
Hamed N, Alahmadi A, Abdelsamad Y, Alballaa A, Almuhawas F, Allami H Sci Rep. 2024; 14(1):9194.
PMID: 38649424 PMC: 11035648. DOI: 10.1038/s41598-024-59295-x.