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Excitation-contraction Uncoupling: Major Role in Contraction-induced Muscle Injury

Overview
Specialty Orthopedics
Date 2001 May 8
PMID 11337828
Citations 89
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Abstract

The mechanisms that account for the strength loss after contraction-induced muscle injury remain controversial. We present data showing that (1) most of the early strength loss results from a failure of excitation-contraction coupling and (2) a slow loss of contractile protein in the days after injury prolongs the recovery time.

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