Major Depression and Quality of Life in Individuals with Multiple Sclerosis

Overview

Journal Int J Psychiatry Med

Publisher Sage Publications

Specialty Psychiatry

Date 2001 Apr 20

PMID 11308035

Citations 20

Authors

J L Wang

M A Reimer

L M Metz

S B Patten

Affiliations

Soon will be listed here.

Abstract

Objective: To compare the Quality of Life (QOL) of multiple sclerosis (MS) patients with and without lifetime major depression.

Method: Data on 136 MS subjects sampled from the University of Calgary MS Clinic were collected. The WHO's Composite International Diagnostic Interview (CIDI) was used to diagnose lifetime major depression. The MSQOL-54 was administered to evaluate QOL of the subjects.

Results: Thirty one (22.8 percent) of the 136 MS subjects had lifetime major depression, However, only 6 of these had a current episode at the time of data collection. MS patients with lifetime major depression had significantly lower MSQOL-54 scores in the QOL domains of Energy, Mental Health, Cognitive Function, General Quality of Life, Sexual Function, and Role Limitation-Emotional than the MS patients without lifetime major depression.

Conclusions: Lifetime major depression may have a substantial impact on the QOL of people with MS. Alternatively, MS patients with poor QOL may be at greater risk of major depression.

Citing Articles

MS care: integrating advanced therapies and holistic management.

Giovannoni G, Ford H, Schmierer K, Middleton R, Stennett A, Pomeroy I Front Neurol. 2024; 14:1286122.

PMID: 38351950 PMC: 10862341. DOI: 10.3389/fneur.2023.1286122.

Adverse childhood experiences in early life increase the odds of depression among adults with multiple sclerosis.

Guerrero K, Horton M, Choudhary V, Bellesis K, Dorin P, Mei J Mult Scler J Exp Transl Clin. 2023; 9(4):20552173231202638.

PMID: 37808459 PMC: 10552460. DOI: 10.1177/20552173231202638.

Comparison of the effectiveness of a tailored cognitive behavioural therapy with a supportive listening intervention for depression in those newly diagnosed with multiple sclerosis (the ACTION-MS trial): protocol of an assessor-blinded, active....

Kiropoulos L, Kilpatrick T, Kalincik T, Churilov L, McDonald E, Wijeratne T Trials. 2020; 21(1):100.

PMID: 31959224 PMC: 6971867. DOI: 10.1186/s13063-019-4018-8.

Cognitive Dysfunctions and Assessments in Multiple Sclerosis.

Oreja-Guevara C, Ayuso Blanco T, Brieva Ruiz L, Hernandez Perez M, Meca-Lallana V, Ramio-Torrenta L Front Neurol. 2019; 10:581.

PMID: 31214113 PMC: 6558141. DOI: 10.3389/fneur.2019.00581.

Diagnoses of Depression and Anxiety Versus Current Symptoms and Quality of Life in Multiple Sclerosis.

Marrie R, Patten S, Berrigan L, Tremlett H, Wolfson C, Warren S Int J MS Care. 2018; 20(2):76-84.

PMID: 29670493 PMC: 5898919. DOI: 10.7224/1537-2073.2016-110.