Retroviruses and the Pathogenesis of Schizophrenia

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 2001 Apr 11

PMID 11296280

Citations 8

Authors

D A Lewis

Affiliations

Soon will be listed here.

Citing Articles

The role of human endogenous retroviruses in the pathogenesis of autoimmune diseases.

Brodziak A, Ziolko E, Muc-Wierzgon M, Nowakowska-Zajdel E, Kokot T, Klakla K Med Sci Monit. 2012; 18(6):RA80-8.

PMID: 22648263 PMC: 3560723. DOI: 10.12659/msm.882892.

The viral theory of schizophrenia revisited: abnormal placental gene expression and structural changes with lack of evidence for H1N1 viral presence in placentae of infected mice or brains of exposed offspring.

Fatemi S, Folsom T, Rooney R, Mori S, Kornfield T, Reutiman T Neuropharmacology. 2011; 62(3):1290-8.

PMID: 21277874 PMC: 3156896. DOI: 10.1016/j.neuropharm.2011.01.011.

Animal models of virus-induced neurobehavioral sequelae: recent advances, methodological issues, and future prospects.

Bortolato M, Godar S Interdiscip Perspect Infect Dis. 2010; 2010:380456.

PMID: 20490350 PMC: 2872755. DOI: 10.1155/2010/380456.

Implication of the env gene of the human endogenous retrovirus W family in the expression of BDNF and DRD3 and development of recent-onset schizophrenia.

Huang W, Li S, Hu Y, Yu H, Luo F, Zhang Q Schizophr Bull. 2010; 37(5):988-1000.

PMID: 20100784 PMC: 3160218. DOI: 10.1093/schbul/sbp166.

Potential microbial origins of schizophrenia and their treatments.

Fatemi S Drugs Today (Barc). 2009; 45(4):305-18.

PMID: 19499095 PMC: 2733838. DOI: 10.1358/dot.2009.45.4.1353924.

References

Tsuang M . Schizophrenia: genes and environment. Biol Psychiatry. 2000; 47(3):210-20. DOI: 10.1016/s0006-3223(99)00289-9. View

Meinl E . Concepts of viral pathogenesis of multiple sclerosis. Curr Opin Neurol. 1999; 12(3):303-7. DOI: 10.1097/00019052-199906000-00009. View

Pulver A . Search for schizophrenia susceptibility genes. Biol Psychiatry. 2000; 47(3):221-30. DOI: 10.1016/s0006-3223(99)00281-4. View

Yolken R, Karlsson H, Yee F, Torrey E . Endogenous retroviruses and schizophrenia. Brain Res Brain Res Rev. 2000; 31(2-3):193-9. DOI: 10.1016/s0165-0173(99)00037-5. View

Lewis D, Lieberman J . Catching up on schizophrenia: natural history and neurobiology. Neuron. 2001; 28(2):325-34. DOI: 10.1016/s0896-6273(00)00111-2. View

Karlsson H, Bachmann S, Schroder J, McArthur J, Torrey E, Yolken R . Retroviral RNA identified in the cerebrospinal fluids and brains of individuals with schizophrenia. Proc Natl Acad Sci U S A. 2001; 98(8):4634-9. PMC: 31886. DOI: 10.1073/pnas.061021998. View

Crow T . A re-evaluation of the viral hypothesis: is psychosis the result of retroviral integration at a site close to the cerebral dominance gene?. Br J Psychiatry. 1984; 145:243-53. DOI: 10.1192/bjp.145.3.243. View

OReilly R, Singh S . Retroviruses and schizophrenia revisited. Am J Med Genet. 1996; 67(1):19-24. DOI: 10.1002/(SICI)1096-8628(19960216)67:1<19::AID-AJMG3>3.0.CO;2-N. View

Patience C, Wilkinson D, Weiss R . Our retroviral heritage. Trends Genet. 1997; 13(3):116-20. DOI: 10.1016/s0168-9525(97)01057-3. View

10.

Nakagawa K, Brusic V, McColl G, Harrison L . Direct evidence for the expression of multiple endogenous retroviruses in the synovial compartment in rheumatoid arthritis. Arthritis Rheum. 1997; 40(4):627-38. DOI: 10.1002/art.1780400407. View

11.

Perron H, Garson J, Bedin F, Beseme F, Paranhos-Baccala G, Komurian-Pradel F . Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. The Collaborative Research Group on Multiple Sclerosis. Proc Natl Acad Sci U S A. 1997; 94(14):7583-8. PMC: 23865. DOI: 10.1073/pnas.94.14.7583. View

12.

Conrad B, Weissmahr R, Boni J, Arcari R, Schupbach J, MACH B . A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetes. Cell. 1997; 90(2):303-13. DOI: 10.1016/s0092-8674(00)80338-4. View

13.

Murphy V, Harrison L, Rudert W, Luppi P, Trucco M, Fierabracci A . Retroviral superantigens and type 1 diabetes mellitus. Cell. 1998; 95(1):9-11; discussion 16. DOI: 10.1016/s0092-8674(00)81775-4. View

14.

Lower R, Tonjes R, Boller K, Denner J, Kaiser B, Phelps R . Development of insulin-dependent diabetes mellitus does not depend on specific expression of the human endogenous retrovirus HERV-K. Cell. 1998; 95(1):11-4; discussion 16. DOI: 10.1016/s0092-8674(00)81776-6. View

15.

Lan M, Mason A, Coutant R, Chen Q, Vargas A, Rao J . HERV-K10s and immune-mediated (type 1) diabetes. Cell. 1998; 95(1):14-6; discussion 16. DOI: 10.1016/s0092-8674(00)81777-8. View