Model Studies for Molecular Recognition of Carbonic Anhydrase and Carboxypeptidase

Overview

Journal Acc Chem Res

Specialty Chemistry

Date 2001 Mar 27

PMID 11263875

Citations 9

Authors

E Kimura

Affiliations

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Abstract

Model studies using Zn(2+) complexes of various derivatives of macrocyclic triamines ([12]aneN(3)) and tetraamines (cyclen) have been found to be useful in elucidating and understanding the intrinsic properties of substrate or inhibitor recognition by zinc ions at the active centers of carbonic anhydrase and carboxypeptidase.

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