An Old Enemy, a New Battle Plan. Perspective on Combating Drug-resistant Malaria

Overview

Journal EMBO Rep

Specialty Molecular Biology

Date 2001 Mar 22

PMID 11258713

Citations 3

Authors

A F Cowman

M T Duraisingh

Affiliations

Soon will be listed here.

Citing Articles

Whole-sporozoite malaria vaccines: where we are, where we are going.

Moita D, Prudencio M EMBO Mol Med. 2024; 16(10):2279-2289.

PMID: 39284948 PMC: 11473726. DOI: 10.1038/s44321-024-00131-0.

Multi-Function of a New Bioactive Secondary Metabolite Derived from Endophytic Fungus of .

Yehia R J Microbiol Biotechnol. 2023; 33(6):806-822.

PMID: 36908276 PMC: 10333465. DOI: 10.4014/jmb.2206.06010.

Characterization of a conserved rhoptry-associated leucine zipper-like protein in the malaria parasite Plasmodium falciparum.

Haase S, Cabrera A, Langer C, Treeck M, Struck N, Herrmann S Infect Immun. 2008; 76(3):879-87.

PMID: 18174339 PMC: 2258820. DOI: 10.1128/IAI.00144-07.

References

Fontanet A, Walker A . Predictors of treatment failure in multiple drug-resistant falciparum malaria: results from a 42-day follow-up of 224 patients in eastern Thailand. Am J Trop Med Hyg. 1993; 49(4):465-72. DOI: 10.4269/ajtmh.1993.49.465. View

Oduola A, Sowunmi A, Milhous W, Brewer T, Kyle D, Gerena L . In vitro and in vivo reversal of chloroquine resistance in Plasmodium falciparum with promethazine. Am J Trop Med Hyg. 1998; 58(5):625-9. DOI: 10.4269/ajtmh.1998.58.625. View

White N . Preventing antimalarial drug resistance through combinations. Drug Resist Updat. 2006; 1(1):3-9. DOI: 10.1016/s1368-7646(98)80208-2. View

Martin S, Oduola A, Milhous W . Reversal of chloroquine resistance in Plasmodium falciparum by verapamil. Science. 1987; 235(4791):899-901. DOI: 10.1126/science.3544220. View

White N, Nosten F, Looareesuwan S, WATKINS W, Marsh K, Snow R . Averting a malaria disaster. Lancet. 1999; 353(9168):1965-7. DOI: 10.1016/s0140-6736(98)07367-x. View

Reed M, Saliba K, Caruana S, Kirk K, Cowman A . Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum. Nature. 2000; 403(6772):906-9. DOI: 10.1038/35002615. View

Wu Y, Kirkman L, Wellems T . Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine. Proc Natl Acad Sci U S A. 1996; 93(3):1130-4. PMC: 40043. DOI: 10.1073/pnas.93.3.1130. View

Fidock D, Nomura T, Talley A, Cooper R, Dzekunov S, Ferdig M . Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance. Mol Cell. 2000; 6(4):861-71. PMC: 2944663. DOI: 10.1016/s1097-2765(05)00077-8. View

Trape J, Pison G, Preziosi M, Enel C, Desgrees du Lou A, Delaunay V . Impact of chloroquine resistance on malaria mortality. C R Acad Sci III. 1998; 321(8):689-97. DOI: 10.1016/s0764-4469(98)80009-7. View

10.

Gardner M, Tettelin H, Carucci D, Cummings L, Aravind L, Koonin E . Chromosome 2 sequence of the human malaria parasite Plasmodium falciparum. Science. 1998; 282(5391):1126-32. DOI: 10.1126/science.282.5391.1126. View

11.

Triglia T, Wang P, Sims P, Hyde J, Cowman A . Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria. EMBO J. 1998; 17(14):3807-15. PMC: 1170716. DOI: 10.1093/emboj/17.14.3807. View