Ibopamine Treatment in Chronic Hypotony Secondary to Long-lasting Uveitis. A Case Report

Purpose: To assess the clinical efficacy of ibopamine eye drops in severe hypotony secondary to chronic progressive uveitis.

Methods: Case report. A 47-year-old man with a 37-year history of diffuse uveitis and severe refractory hypotony was treated with topical 2% ibopamine (Trazyl) six times a day. Intraocular pressure, visual acuity, visual field and side effects were recorded during 15 months of follow-up.

Results: IOP, visual acuity and visual field increased after four days of therapy and lasted for two months when the drug was suspended because of the onset of filamentous keratopathy. A new course of treatment with 2% ibopamine eye drops in a different solvent (BSS) resulted in a stable increase in IOP, VA and visual field, with no side effects in a follow-up of 13 months.

Conclusions: Ibopamine 2% eye drops in BSS solvent seem effective in the treatment of uveitis-related hypotony.