External Quality Assessment of Bone Metabolism Marker Assays. Initial Experiences in a UK NEQAS Programme

Overview

Journal Clin Chem Lab Med

Specialties Biochemistry
Pathology

Date 2001 Jan 13

PMID 11156340

Citations 2

Authors

K M Whitham

Affiliations

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Abstract

This paper reports on a pilot external quality assessment scheme for bone markers including serum bone alkaline phosphatase and procollagen 1-carboxy terminal propeptide together with urine deoxypyridinoline, N- and C-telopeptides. The data shows poor numerical agreement between commercial assays, between-laboratory imprecision that could be improved, and the need for international standardisation of assays.

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