Quantitative Hemoglobin Tomography with Diffuse Near-infrared Spectroscopy: Pilot Results in the Breast

Overview

Journal Radiology

Specialty Radiology

Date 2001 Jan 12

PMID 11152812

Citations 95

Authors

B W Pogue

S P Poplack

T O McBride

W A Wells

K S Osterman

U L Osterberg

K D Paulsen

Affiliations

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Abstract

The authors describe what is, to the best of their knowledge, the first quantitative hemoglobin concentration images of the female breast that were formed with model-based reconstruction of near-infrared intensity-modulated tomographic data. The results in 11 patients, including two with breast tumors with pathologic correlation, are summarized. Hemoglobin concentration appears to correlate with tumor vascularity without the need for exogenous contrast material and thereby has intrinsic diagnostic value.

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