The Spindle Cycle in Budding Yeast

Overview

Journal Nat Cell Biol

Specialty Cell Biology

Date 2001 Jan 9

PMID 11146646

Citations 82

Authors

M Winey

E T OToole

Affiliations

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Abstract

The mitotic spindle of the budding yeast Saccharomyces cerevisiae will probably be the first such organelle to be understood in molecular detail. Here we describe the mitotic spindle cycle of budding yeast using electron-microscope-derived structures and dynamic live-cell imaging. Recent work has revealed that many general aspects of mitosis are conserved, making budding yeast an excellent model for the study of mitosis.

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