Isolation of Galantins I and II, Water-soluble Basic Peptides. Studies on Antibiotics from the Genus Bacillus. III

Overview

Journal J Antibiot (Tokyo)

Specialties Infectious Diseases
Pharmacology

Date 1975 Feb 1

PMID 1112763

Citations 4

Authors

J Shoji

R Sakazaki

Y Wakisaka

K Koizumi

M MAYAMA

S Matsuura

Affiliations

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Abstract

Two water-soluble basic antibiotics named galantins I and II were isolated from a strain resembling Bacillus pulvifaciens. Both antibiotics are peptides containing glycine, alanine, ornithine, lysine and some unknown ninhydrin-positive components. An approximate empirical formula C50 plus and minus H98plus and minus 2O17N16 is indicated for galantin I. These are active against some gram-positive, acid-fast and gram-negative bacteria.

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