Spontaneous Intracranial Bleeding in Two Patients with Congenital Afibrinogenaemia and the Role of Replacement Therapy

Overview

Journal Haemophilia

Specialty Hematology

Date 2000 Dec 21

PMID 11122402

Citations 6

Authors

R Parameswaran

J P Dickinson

S de Lord

D M Keeling

B T Colvin

Affiliations

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Abstract

Congenital afibrinogenaemia and hypofibrinogenaemia are rare disorders of haemostasis. In this case report the problems posed in the management of two patients with fibrinogen levels less than 0.1g L(-1) and who developed intracranial bleeding are considered. The value of fibrinogen concentrate and the role of prophylaxis is also discussed.

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