Growth of Thrombus May Be a Better Predictor of Rupture Than Diameter in Patients with Abdominal Aortic Aneurysms

Overview

Journal Eur J Vasc Endovasc Surg

Publisher Elsevier

Specialties Cardiology & Vascular Diseases
Gastroenterology
General Surgery

Date 2000 Dec 9

PMID 11112467

Citations 51

Authors

J Stenbaek

B Kalin

J Swedenborg

Affiliations

Soon will be listed here.

Abstract

Objectives: to investigate the relationships between diameter, surface and thrombus area in abdominal aortic aneurysms (AAAs) <5 cm.

Methods And Material: sixty-seven patients with AAA underwent at least 2 CT examinations. At the point of maximal diameter, surface area and thrombus area were calculated and related to rupture, or impending rupture, during follow-up.

Results: the mean increase in measured diameter, surface area and thrombus area were 3.4 mm, 1.9 cm(2)and 1.7 cm(2)per year respectively. Patients with AAA >4 cm and whose thrombus area increased >1.5 cm(2)/year were more likely to rupture (6/24 vs 1/23).

Conclusions: a rapid increase of thrombus area may be a better predictor of AAA rupture than increase in maximal diameter.

Citing Articles

Relationship Between Intraluminal Thrombus Volume and Circulating ADAMTS-13 Activity in Abdominal Aortic Aneurysms.

Ghulam Q, Goetze J, Eldrup N, Eiberg J EJVES Vasc Forum. 2024; 62:41-45.

PMID: 39328304 PMC: 11426131. DOI: 10.1016/j.ejvsvf.2024.07.040.

Soluble glycoprotein VI predicts abdominal aortic aneurysm growth rate and is a novel therapeutic target.

Benson T, Pike M, Spuzzillo A, Hicks S, Ali S, Pham M Blood. 2024; 144(16):1663-1678.

PMID: 38900973 PMC: 11522893. DOI: 10.1182/blood.2023021655.

Open repair of an abdominal aortic and right common iliac artery aneurysm with idiopathic retroperitoneal fibrosis in a 19-month-old infant.

Chamseddin K, Solano A, Keller M, Siah M, Gonzalez-Guardiola G, Prakash V J Vasc Surg Cases Innov Tech. 2024; 10(4):101513.

PMID: 38868166 PMC: 11167345. DOI: 10.1016/j.jvscit.2024.101513.

Relative Thrombus Burden Ratio Reveals Overproportioned Intraluminal Thrombus Growth-Potential Implications for Abdominal Aortic Aneurysm.

Mulorz J, Mazrekaj A, Sehl J, Arnautovic A, Garabet W, Krott K J Clin Med. 2024; 13(4).

PMID: 38398275 PMC: 10889130. DOI: 10.3390/jcm13040962.

Mechanism of sac expansion without evident endoleak analyzed with X ray phase-contrast tomography.

Yamamoto T, Tsukube T, Wada Y, Hoshino M, Yagi N, Nakagawa K JVS Vasc Sci. 2023; 4:100123.

PMID: 37662587 PMC: 10474490. DOI: 10.1016/j.jvssci.2023.100123.