Quantitative Studies of Pinocytosis. I. Kinetics of Uptake of (125I)polyvinylpyrrolidone by Rat Yolk Sac Cultured in Vitro

Overview

Journal J Cell Biol

Specialty Cell Biology

Date 1975 Jan 1

PMID 1109230

Citations 27

Authors

K E Williams

E M Kidston

F Beck

J B Lloyd

Affiliations

Soon will be listed here.

Abstract

A method is described for the in vitro culture of 17.5-day rat visceral yolk sac. Tissue survival was good as judged by light and electron microscopy. The rate of pinocytic uptake of 125I-labeled polyvinylpyrrolidone by the tissue was constant both within and between experiments. Within the concentration range 0.15-24 mug/ml, the 125I-labeled polyvinylpyrrolidone neither stimulated nor inhibited pinocytosis. The system offers many advantages in the quantitative study of the physical basis of pinocytosis.

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