Physical Injury As a Provoking Factor in Three Patients with Scleroderma
Overview
Affiliations
A 51-year-old female developed linear-like scleroderma in the left thigh following a linear wound caused by a car accident. 27 years later she also developed a typical diffuse cutaneous systemic sclerosis with extensive skin involvement and bibasilar pulmonary fibrosis. The second case is a 39-year-old female who had a history of Raynaud's phenomenon since early childhood. She developed a morphea following a burning injury of the left thigh. 17 years later she also developed a typical limited cutaneous systemic sclerosis with sclerodactyly, skin ulcers and subcutaneous calcinosis. The third case is a 43-year-old female who developed a typical morphea of the right elbow around the site of a previous local corticosteroid injection. The two remarkable points of these 3 cases are the possible role of physical injury in the provocation of localized scleroderma and in the first 2 cases the unusual later development of a systemic form of scleroderma.
Localized scleroderma: clinical spectrum and therapeutic update.
Careta M, Romiti R An Bras Dermatol. 2015; 90(1):62-73.
PMID: 25672301 PMC: 4323700. DOI: 10.1590/abd1806-4841.20152890.