Replication of PhiA and PhiX174 in Escherichia Coli Mutants Thermosensitive in DNA Synthesis

Overview

Journal Mol Gen Genet

Specialties Genetics
Molecular Biology

Date 1975 Sep 8

PMID 1102942

Citations 10

Authors

A TAKETO

Affiliations

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Abstract

Thermosensitive mutants of E. coli defective in DNA replication were tested for their capacity to support multiplication of phiA and phiX174. At the restrictive temperature, the viral growth was markedly affected in dnaH, dnaZ, or ligts7 mutants. Even when these strains were transfected with RF1 molecules, the virus yield was still very low. The dnaI function was, however, dispensable for replication of phiA and phiX174. In addition, these viruses could multiply in dnaP or polAts mutants at the high temperature.

Citing Articles

Host genes involved in the replication of single-stranded DNA phage phiK.

TAKETO A Mol Gen Genet. 1976; 148(1):25-9.

PMID: 792679 DOI: 10.1007/BF00268542.

Deoxyribonucleic acid synthesis in a temperature-sensitive Escherichia coli dnaH mutant, strain HF4704S.

Derstine P, Dumas L J Bacteriol. 1976; 128(3):801-9.

PMID: 791933 PMC: 232771. DOI: 10.1128/jb.128.3.801-809.1976.

Mechanism of DNA elongation catalyzed by Escherichia coli DNA polymerase III, dnaZ protein, and DNA elongation factors I and III.

Wickner S Proc Natl Acad Sci U S A. 1976; 73(10):3511-5.

PMID: 790389 PMC: 431146. DOI: 10.1073/pnas.73.10.3511.

Host factor requirements and some properties of phiXtB. An evolutionary aspect of phiX-type phages.

TAKETO A Mol Gen Genet. 1976; 148(2):139-42.

PMID: 790153 DOI: 10.1007/BF00268377.

DNA synthesis in vitro dependent upon phiX174 replicative form I DNA.

Yudelevich A, Hurwitz J Proc Natl Acad Sci U S A. 1976; 73(6):1887-91.

PMID: 778850 PMC: 430412. DOI: 10.1073/pnas.73.6.1887.

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