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Methionine Biosynthesis in Saccharomyces Cerevisiae. I. Genetical Analysis of Auxotrophic Mutants

Overview
Journal Mol Gen Genet
Specialties Genetics
Molecular Biology
Date 1975 Aug 5
PMID 1101032
Citations 59
Authors
M Masselot
H DE ROBICHON-SZULMAJSTER
Affiliations
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Abstract

In order to analyse how many structural genes are implicated in the specific steps of the biosynthesis of methionine in Sacch. cerevisiae, a hundred mutants were studied by complementation. 21 groups were defined named MET1 to MET25. Neither recombination between independent mutants of the same complementation group nor linkage between different groups was found. Preliminary to biochemical studies, mutants of each complementation group were tested for their capacity to utilize various precursors of methionine.

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References
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