Therapy for H. Pylori Infection
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Abstract
The discovery that peptic ulcers can be caused by gastroduodenal infection with Helicobacter pylori and cured by eradication of this bacterial presence has made a profound impact on ulcer management. This article reviews the principles behind such treatment and the regimens in current use, including proton pump inhibitor triple therapies and ranitidine bismuth citrate triple therapies.
References
1.
Ducons J, Santolaria S, Guirao R, Ferrero M, Montoro M, Gomollon F
. Impact of clarithromycin resistance on the effectiveness of a regimen for Helicobacter pylori: a prospective study of 1-week lansoprazole, amoxycillin and clarithromycin in active peptic ulcer. Aliment Pharmacol Ther. 1999; 13(6):775-80.
DOI: 10.1046/j.1365-2036.1999.00549.x.
View
2.
Veldhuyzen van Zanten S, Sherman P
. Helicobacter pylori infection as a cause of gastritis, duodenal ulcer, gastric cancer and nonulcer dyspepsia: a systematic overview. CMAJ. 1994; 150(2):177-85.
PMC: 1486230.
View
3.
Laine L, Hopkins R, Girardi L
. Has the impact of Helicobacter pylori therapy on ulcer recurrence in the United States been overstated? A meta-analysis of rigorously designed trials. Am J Gastroenterol. 1998; 93(9):1409-15.
DOI: 10.1111/j.1572-0241.1998.452_a.x.
View
4.
Huang J, Hunt R
. The importance of clarithromycin dose in the management of Helicobacter pylori infection: a meta-analysis of triple therapies with a proton pump inhibitor, clarithromycin and amoxycillin or metronidazole. Aliment Pharmacol Ther. 1999; 13(6):719-29.
DOI: 10.1046/j.1365-2036.1999.00530.x.
View
5.
Hawkey C, Karrasch J, SZCZEPANSKI L, Walker D, Barkun A, Swannell A
. Omeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs. Omeprazole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) Study Group. N Engl J Med. 1998; 338(11):727-34.
DOI: 10.1056/NEJM199803123381105.
View