LAP Proteins: What's Up with Epithelia?

Overview

Journal Nat Cell Biol

Specialty Cell Biology

Date 2000 Aug 10

PMID 10934483

Citations 17

Authors

P J Bryant

A Huwe

Affiliations

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Abstract

How cells maintain their overall shape and size, and the related question of how proteins and other molecules reach and stay at their specific subcellular locations, are among the most difficult and exciting problems in cell biology. Three recent studies have made a significant contribution to this area by identifying new proteins, called LAP proteins, that have critical functions in maintaining the shape and apical-basal polarity of epithelial cells.

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