Yttrium Radiosynoviorthesis in the Treatment of Knee Arthritis in Rheumatoid Arthritis: a Systematic Review

Overview

Journal Ann Rheum Dis

Specialty Rheumatology

Date 2000 Jul 27

PMID 10913051

Citations 19

Authors

L L Heuft-Dorenbosch

H C de Vet

S van der Linden

Affiliations

Soon will be listed here.

Abstract

Objective: To consider the question: How strong is the evidence in favour of yttrium synovectomy in chronic knee arthritis in patients with rheumatoid arthritis in comparison with placebo and intra-articular steroid treatment?

Methods: A systematic review of the literature was performed using Medline and the Embase database.

Results: Initially, seven papers were identified, but only two met the inclusion criteria. Neither study showed evidence in favour of yttrium synovectomy.

Conclusion: From the point of view of evidence based medicine it should be seriously questioned whether yttrium synovectomy deserves a place in clinical practice.

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References

Delbarre F, Cayla J, Menkes C, Aignan M, Roucayrol J, INGRAND J . [Synoviorthesis with radioisotopes]. Presse Med (1893). 1968; 76(22):1045-50. View

Verhagen A, de Vet H, de Bie R, Kessels A, Boers M, Bouter L . The Delphi list: a criteria list for quality assessment of randomized clinical trials for conducting systematic reviews developed by Delphi consensus. J Clin Epidemiol. 1999; 51(12):1235-41. DOI: 10.1016/s0895-4356(98)00131-0. View

Bridgman J, Bruckner F, Eisen V, Tucker A, Bleehen N . Irradiation of the synovium in the treatment of rheumatoid arthritis. Q J Med. 1973; 42(166):357-67. View

Gumpel J, Roles N . A controlled trial of intra-articular radiocolloids versus surgical synovectomy in persistent synovitis. Lancet. 1975; 1(7905):488-9. DOI: 10.1016/s0140-6736(75)92832-9. View

Vignon G, Colcombet P, LAHNECHE B, Bied J, Meunier P . [Comparison of osmic and isotopic synoviorthesis in rheumatoid arthritis]. Nouv Presse Med. 1974; 3(45):2712-4. View

Delbarre F, Le Go A, Menkes C, Aignan M . [Double blind statistical study of therapeutic effect of a radioactivy yttrium (90Y) charged colloid on rheumatoid arthritis of the knee]. C R Acad Hebd Seances Acad Sci D. 1974; 279(12):1051-4. View

Muller W, Pavelka K, Fridrich R . Treatment of chronic articular effusions with 90-yttrium (90Y). Scand J Rheumatol. 1975; 4(4):216-20. DOI: 10.3109/03009747509165259. View

Szanto E . Long-term follow-up of 90Yttrium-treated knee-joint arthritis. Scand J Rheumatol. 1977; 6(4):209-12. DOI: 10.3109/03009747709095451. View

Nissila M, Anttila P, Hamalainen M, Jalava S . Comparison of chemical, radiation and surgical synovectomy for knee joint synovitis. Scand J Rheumatol. 1978; 7(4):225-8. DOI: 10.3109/03009747809095660. View

10.

Reichel H, Bergmann H, Kolarz G, Thumb N . [Radiosynoviorthesis with yttrium-90-silicate. Results compared to aurum-198-colloid and whole body radiation load]. Acta Med Austriaca. 1979; 6(1):19-25. View

11.

Sheppeard H, Aldin A, WARD D . Osmic acid versus yttrium-90 in rheumatoid synovitis of the knee. Scand J Rheumatol. 1981; 10(3):234-6. DOI: 10.3109/03009748109095304. View

12.

Boerbooms A, Buijs W, Danen M, van de Putte L, Vandenbroucke J . Radio-synovectomy in chronic synovitis of the knee joint in patients with rheumatoid arthritis. Eur J Nucl Med. 1985; 10(9-10):446-9. DOI: 10.1007/BF00256588. View

13.

Jones G . Yttrium synovectomy: a meta-analysis of the literature. Aust N Z J Med. 1993; 23(3):272-5. DOI: 10.1111/j.1445-5994.1993.tb01731.x. View

14.

Deutsch E, Brodack J, Deutsch K . Radiation synovectomy revisited. Eur J Nucl Med. 1993; 20(11):1113-27. DOI: 10.1007/BF00173494. View

15.

Clunie G, Ell P . A survey of radiation synovectomy in Europe, 1991-1993. Eur J Nucl Med. 1995; 22(9):970-6. DOI: 10.1007/BF00808407. View

16.

Wilke W . Innovative treatment approaches for rheumatoid arthritis. Non-surgical synovectomy. Baillieres Clin Rheumatol. 1995; 9(4):787-801. DOI: 10.1016/s0950-3579(05)80314-0. View

17.

Bridgman J, Bruckner F, Bleehen N . Radioactive yttrium in the treatment of rheumatoid knee effusions. Preliminary evaluation. Ann Rheum Dis. 1971; 30(2):180-2. PMC: 1005747. DOI: 10.1136/ard.30.2.180. View