Mapping of the Gene for Glutathione Reductase on Chromosome 8

Overview

Journal Ann Genet

Publisher Elsevier

Specialty Genetics

Date 1976 Dec 1

PMID 1087855

Citations 10

Authors

A de la Chapelle

A Icen

P AULA

J Leisti

C Turleau

J de Grouchy

Affiliations

Soon will be listed here.

Abstract

Red cell glutathione reductase (E-GSR) activity in 3 patients with mos46,XY/47,XY,+8 was higher than the mean value in controls, confirming the previous assignment of the E-GSR locus to chromosome 8. In a infant with a terminal deletion of the short arm of chromosome 8, 46,XX,del(8)(:p21 leads to qter), E-GSR activity was markedly lower than in infant controls. The authors suggest that the E-GSR locus is in the region 8p21 leads to pter.

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