Role of C282Y Mutation in Haemochromatosis Gene in Development of Type 2 Diabetes in Healthy Men: Prospective Cohort Study

Overview

Journal BMJ

Specialty General Medicine

Date 2000 Jun 23

PMID 10864547

Citations 8

Authors

J T Salonen

T P Tuomainen

K Kontula

Affiliations

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Citing Articles

[Molecular genetic analysis and clinical aspects of patients with hereditary hemochromatosis].

Lange U, Teichmann J, Dischereit G Orthopade. 2014; 43(8):772-9.

PMID: 24906241 DOI: 10.1007/s00132-014-2318-y.

Diabetes and hemochromatosis.

Creighton Mitchell T, McClain D Curr Diab Rep. 2014; 14(5):488.

PMID: 24682660 DOI: 10.1007/s11892-014-0488-y.

Hereditary hemochromatosis and diabetes mellitus: implications for clinical practice.

Utzschneider K, Kowdley K Nat Rev Endocrinol. 2009; 6(1):26-33.

PMID: 20010968 DOI: 10.1038/nrendo.2009.241.

Clinical manifestations of hemochromatosis in HFE C282Y homozygotes identified by screening.

McLaren G, McLaren C, Adams P, Barton J, Reboussin D, Gordeuk V Can J Gastroenterol. 2008; 22(11):923-30.

PMID: 19018338 PMC: 2661195. DOI: 10.1155/2008/907356.

Haemochromatosis gene mutations and risk of coronary heart disease: a west of Scotland coronary prevention study (WOSCOPS) substudy.

Gunn I, Maxwell F, Gaffney D, McMahon A, Packard C Heart. 2004; 90(3):304-6.

PMID: 14966054 PMC: 1768115. DOI: 10.1136/hrt.2003.015149.

References

Yaouanq J . Diabetes and haemochromatosis: current concepts, management and prevention. Diabete Metab. 1995; 21(5):319-29. View

Feder J, Gnirke A, Thomas W, Tsuchihashi Z, Ruddy D, Basava A . A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet. 1996; 13(4):399-408. DOI: 10.1038/ng0896-399. View

Merryweather-Clarke A, Pointon J, Shearman J, Robson K . Global prevalence of putative haemochromatosis mutations. J Med Genet. 1997; 34(4):275-8. PMC: 1050911. DOI: 10.1136/jmg.34.4.275. View

Tuomainen T, Kontula K, Nyyssonen K, Lakka T, Helio T, Salonen J . Increased risk of acute myocardial infarction in carriers of the hemochromatosis gene Cys282Tyr mutation : a prospective cohort study in men in eastern Finland. Circulation. 1999; 100(12):1274-9. DOI: 10.1161/01.cir.100.12.1274. View

Salonen J, Nyyssonen K, Tuomainen T, Maenpaa P, Korpela H, Kaplan G . Increased risk of non-insulin dependent diabetes mellitus at low plasma vitamin E concentrations: a four year follow up study in men. BMJ. 1995; 311(7013):1124-7. PMC: 2551054. DOI: 10.1136/bmj.311.7013.1124. View