Positive Correlation Between Virulence of Pseudomonas Aeruginosa Mutants in Mice and Insects

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 2000 Jun 13

PMID 10851003

Citations 250

Authors

G Jander

L G Rahme

F M Ausubel

Affiliations

Soon will be listed here.

Abstract

Strain PA14, a human clinical isolate of Pseudomonas aeruginosa, is pathogenic in mice and insects (Galleria mellonella). Analysis of 32 different PA14 mutants in these two hosts showed a novel positive correlation in the virulence patterns. Thus, G. mellonella is a good model system for identifying mammalian virulence factors of P. aeruginosa.

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