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Medical Problems of Surgical Patients. Hypertension and Ischaemic Heart Disease

Overview
Specialty General Surgery
Date 1976 Nov 1
PMID 10825
Citations 1
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Abstract

Pre-existing disease in the form of hypertension or ischaemic heart disease may increase morbidity and mortality in patients presenting for anaesthesia and surgery. The interaction of these two cardiovascular conditions in relation to anaesthesia has been studied in a series of 115 patients. The results did not support the view that antihypertensive drugs and beta-receptor blocking agents should be withdrawn before anaesthesia and surgery. The main cause for concern in providing anaesthesia for these patients is that sympathetic nervous activation induced either by anaesthetic manoeuvres or by surgical stimulation may lead to reflex cardiovascular responses which, by increasing myocardial oxygen demand, lead to episodes of myocardial ischaemia. In this respect beta-receptor blocking drugs appear to have a protective effect on the ischaemic myocardium.

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References
1.
HICKLER R, Vandam L . Hypertension. Anesthesiology. 1970; 33(2):214-28. DOI: 10.1097/00000542-197008000-00015. View

2.
Dingle H . Antihypertensive drugs and anaesthesia. Anaesthesia. 1966; 21(2):151-72. DOI: 10.1111/j.1365-2044.1966.tb02595.x. View

3.
Mauney Jr F, Ebert P, SABISTON Jr D . Postoperative myocardial infarction: a study of predisposing factors, diagnosis and mortality in a high risk group of surgical patients. Ann Surg. 1970; 172(3):497-503. PMC: 1397340. DOI: 10.1097/00000658-197009000-00013. View

4.
Caralps J, Mulet J, Wienke H, Moran J, Pifarre R . Results of coronary artery surgery in patients receiving propranolol. J Thorac Cardiovasc Surg. 1974; 67(4):526-9. View

5.
Prys-Roberts C, Foex P, GREENE L, Waterhouse T . Studies of anaesthesia in relation to hypertension. IV. The effects of artificial ventilation on the circulation and pulmonary gas exchanges. Br J Anaesth. 1972; 44(4):335-49. DOI: 10.1093/bja/44.4.335. View