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Detection of 23 Immunogenic Pneumococcal Proteins Using Convalescent-phase Serum

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Journal Infect Immun
Date 2000 May 19
PMID 10816539
Citations 22
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Abstract

A genomic expression library of Streptococcus pneumoniae was screened with a convalescent-phase serum for immunoreactive proteins. Six known and 17 unknown pneumococcal proteins were detected. Five of the known proteins were surface-located virulence factors, and eight of the unknown proteins were putative membrane proteins.

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