Phospholipase A2 and Its Potential Regulation of Islet Function

Overview

Journal Int J Pancreatol

Specialty Gastroenterology

Date 2000 May 16

PMID 10811018

Citations 6

Authors

E SIMONSSON

B Ahren

Affiliations

Soon will be listed here.

Citing Articles

Comparison of the efficacy of sitagliptin and glimepiride dose-up in Japanese patients with type 2 diabetes poorly controlled by sitagliptin and glimepiride in combination.

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Group VIA PLA2 (iPLA2β) is activated upstream of p38 mitogen-activated protein kinase (MAPK) in pancreatic islet β-cell signaling.

Song H, Wohltmann M, Tan M, Bao S, Ladenson J, Turk J J Biol Chem. 2011; 287(8):5528-41.

PMID: 22194610 PMC: 3285329. DOI: 10.1074/jbc.M111.285114.

Insulin secretory responses and phospholipid composition of pancreatic islets from mice that do not express Group VIA phospholipase A2 and effects of metabolic stress on glucose homeostasis.

Bao S, Song H, Wohltmann M, Ramanadham S, Jin W, Bohrer A J Biol Chem. 2006; 281(30):20958-20973.

PMID: 16732058 PMC: 2044498. DOI: 10.1074/jbc.M600075200.

Effects of stable suppression of Group VIA phospholipase A2 expression on phospholipid content and composition, insulin secretion, and proliferation of INS-1 insulinoma cells.

Bao S, Bohrer A, Ramanadham S, Jin W, Zhang S, Turk J J Biol Chem. 2005; 281(1):187-98.

PMID: 16286468 PMC: 2156593. DOI: 10.1074/jbc.M509105200.

Pancreatic islets and insulinoma cells express a novel isoform of group VIA phospholipase A2 (iPLA2 beta) that participates in glucose-stimulated insulin secretion and is not produced by alternate splicing of the iPLA2 beta transcript.

Ramanadham S, Song H, Hsu F, Zhang S, Crankshaw M, Grant G Biochemistry. 2003; 42(47):13929-40.

PMID: 14636061 PMC: 3716001. DOI: 10.1021/bi034843p.

References

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