Sister Chromatid Cohesion: the Beginning of a Long and Beautiful Relationship

Overview

Journal Curr Opin Cell Biol

Publisher Elsevier

Specialty Cell Biology

Date 2000 May 10

PMID 10801457

Citations 43

Authors

D E Koshland

V Guacci

Affiliations

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Abstract

Our understanding of the mechanism of sister chromatid cohesion has advanced significantly with the recent identification and characterization of important regulatory factors, structural factors and chromosomal cohesion sites. These analyses reveal a surprisingly complex mechanism of cohesion that is just beginning to be elucidated and exciting connections between cohesion, cell-cycle regulation and other forms of DNA metabolism.

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