T-cell Memory: Lessons from Epstein-Barr Virus Infection in Man

Overview

Journal Philos Trans R Soc Lond B Biol Sci

Specialty Biology

Date 2000 May 4

PMID 10794060

Citations 13

Authors

A B Rickinson

M F Callan

N E Annels

Affiliations

Soon will be listed here.

Abstract

Epstein-Barr virus offers an ideal opportunity to follow the human T-cell response to a virus infection over time from its acute primary phase, as seen in infectious mononucleosis patients, into the memory phase that accompanies life-long virus persistence. Here we review recent evidence on the development and maturation of cytotoxic T-cell memory using this viral system.

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