Gender Differences in Regional Cerebral Activity During Sadness

Overview

Journal Hum Brain Mapp

Publisher Wiley

Specialty Neurology

Date 2000 Apr 19

PMID 10770231

Citations 27

Authors

F Schneider

U Habel

C Kessler

J B Salloum

S Posse

Affiliations

Soon will be listed here.

Abstract

Functional magnetic resonance imaging and echo-planar-imaging were used to investigate affect related gender differences in regional cerebral activity. The experiment was conducted using a standardized mood induction procedure. Blood-oxygen-level-dependent effect was measured in 13 male and 13 female healthy subjects, during both moods of happiness and sadness, respectively. Parallel to earlier neuroimaging findings, our results show brain activity in the amygdala of males during negative affect. Females failed to demonstrate a similar activation pattern despite matched subjective ratings of negative affect to males. Results point to differential regional cerebral correlates of emotional experience in males and females, which is suggestive of a more focal and subcortical processing of sadness in men.

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