In Vivo-induced Genes in Pseudomonas Aeruginosa

Overview

Journal Infect Immun

Publisher American Society for Microbiology

Specialty Allergy & Immunology

Date 2000 Mar 18

PMID 10722644

Citations 17

Authors

M Handfield

D E Lehoux

F Sanschagrin

M J Mahan

D E Woods

R C Levesque

Affiliations

Soon will be listed here.

Abstract

In vivo expression technology was used for testing Pseudomonas aeruginosa in the rat lung model of chronic infection and in a mouse model of systemic infection. Three of the eight ivi proteins found showed sequence identity to known virulence factors involved in iron acquisition via an open reading frame (called pvdI) implicated in pyoverdine biosynthesis, membrane biogenesis (FtsY), and adhesion (Hag2).

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