Hypoglycaemic and Other Related Actions of Tinospora Cordifolia Roots in Alloxan-induced Diabetic Rats

Overview

Journal J Ethnopharmacol

Date 2000 Mar 18

PMID 10720784

Citations 38

Authors

P Stanely

M Prince

V P Menon

Affiliations

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Abstract

Tinospora cordifolia is widely used in Indian Ayurvedic medicine for treating diabetes mellitus. Oral administration of an aqueous T. cordifolia root extract (TCREt) to alloxan diabetic rats caused a significant reduction in blood glucose and brain lipids. The extract caused an increase in body weight, total haemoglobin and hepatic hexokinase. The root extract also lowers hepatic glucose-6-phosphatase and serum acid phosphatase, alkaline phosphatase, and lactate dehydrogenase in diabetic rats. Thus TCREt has hypoglycaemic and hypolipidaemic effect.

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