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Notch Signaling in T Cell Development

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Publisher Elsevier
Date 2000 Mar 14
PMID 10712939
Citations 43
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Abstract

Notch signaling regulates cell fate decisions during development. Recent experiments suggest that Notch signaling is essential for initial commitment to the T cell lineage and may function together with signals from the pre-TCR and the TCR to regulate subsequent steps of T cell development.

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