Steroids from Harrisonia Abyssinica
Overview
Affiliations
In addition to the known sterols and ketosteroids beta-sitosterol (24 alpha-ethylcholest-5-en-3 beta-ol), stigmasterol (24 alpha-ethylcholesta-5,22-dien-3 beta-ol), campesterol (24 alpha-methylcholest-5-en-3 beta-ol), beta-sitostenone (stigmast-4-en-3-one, 24 alpha-ethylcholest-4-en-3-one), stigmastenone (stigmasta-4,22-dien-3-one, 24 alpha-ethylcholesta-4,22-dien-3-one), campestenone (24 alpha-methylcholest-4-en-3-one), and stigmasta-3,5-dien-7-one (24 alpha-ethylcholesta-3,5-dien-7-one), the new steroids stigmasta-3,5,22-trien-7-one (24 alpha-ethylcholesta-3,5,22-trien-7-one), and campesta-3,5-dien-7-one (24 alpha-methylcholesta-3,5-dien-7-one) were isolated from the stem bark of Harrisonia abyssinica and identified by NMR and mass spectrometry.
Lan Y, Chen I, Lu H, Guo T, Hwang T, Leu Y Molecules. 2022; 27(6).
PMID: 35335252 PMC: 8954059. DOI: 10.3390/molecules27061885.
Park S, Kim Y, Park M, Byun S, Kim S, Lee J Inflammation. 2015; 39(2):727-34.
PMID: 26707503 DOI: 10.1007/s10753-015-0299-6.
Li W, Lin Y, Wu P, Wen Z, Liu P, Chen C Int J Mol Sci. 2013; 14(1):1698-712.
PMID: 23322020 PMC: 3565342. DOI: 10.3390/ijms14011698.