CD10 Positive Thyroid Marginal Zone Non-Hodgkin Lymphoma

Overview

Journal J Clin Pathol

Specialty Pathology

Date 2000 Feb 26

PMID 10690178

Citations 7

Authors

E K Millar

S Waldron

A Spencer

S Braye

Affiliations

Soon will be listed here.

Abstract

A 72 year old woman presented with swelling of the right lobe of her thyroid gland. Fine needle aspiration and flow cytometry showed a clonal population of B cells expressing CD10 and a diagnosis of follicle centre cell lymphoma was made. Subsequent excision of the thyroid showed the typical histological features of a marginal zone non-Hodgkin lymphoma. Polymerase chain reaction showed no evidence of t (14;18). Immunohistochemistry confirmed CD10 positivity and LN1 (CDw75) expression. This is only the second report of aberrant expression of CD 10 by a marginal zone lymphoma.

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