A Portrait of the Bcl-2 Protein Family: Life, Death, and the Whole Picture

Overview

Journal J Clin Immunol

Publisher Springer

Specialty Allergy & Immunology

Date 2000 Jan 14

PMID 10634210

Citations 12

Authors

M Pellegrini

A Strasser

Affiliations

Soon will be listed here.

Abstract

The Bcl-2 family of proteins are important regulators of cell death. They are comprised of two opposing factions, the proapoptotic versus the antiapoptotic members. Both are required for normal development and cellular homeostasis of the immune system and other tissues. However, in certain circumstances they may participate in the development of disease.

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