OpdA, a Salmonella Enterica Serovar Typhimurium Gene Encoding a Protease, is Part of an Operon Regulated by Heat Shock
Overview
Authors
Affiliations
The opdA (prlC) gene of Salmonella enterica serovar Typhimurium and Escherichia coli encodes the metalloprotease oligopeptidase A (OpdA). We report that opdA is cotranscribed with a downstream open reading frame, yhiQ. Transcription of this operon is induced after a temperature shift (30 to 42 degrees C), and this induction depends on the heat shock sigma factor encoded by the rpoH (htpR) gene.
Anu P, Madanan M, Nair A, Nair G, Nair G, Sudhakaran P Mol Biotechnol. 2018; 60(4):302-309.
PMID: 29502205 DOI: 10.1007/s12033-018-0073-8.
Atas A, Seddon A, Ford D, Cooper I, Wren B, Oyston P BMC Microbiol. 2016; 16(1):282.
PMID: 27887582 PMC: 5124237. DOI: 10.1186/s12866-016-0900-7.
Muller A, Hoffmann J, Meyer H, Narberhaus F, Jakob U, Leichert L J Bacteriol. 2013; 195(12):2807-16.
PMID: 23585533 PMC: 3697257. DOI: 10.1128/JB.00127-13.
YhiQ is RsmJ, the methyltransferase responsible for methylation of G1516 in 16S rRNA of E. coli.
Basturea G, Dague D, Deutscher M, Rudd K J Mol Biol. 2011; 415(1):16-21.
PMID: 22079366 PMC: 4140241. DOI: 10.1016/j.jmb.2011.10.044.
Price M, Arkin A, Alm E PLoS Genet. 2006; 2(6):e96.
PMID: 16789824 PMC: 1480536. DOI: 10.1371/journal.pgen.0020096.