Haematological Disease in Siblings with Rothmund-Thomson Syndrome

Overview

Journal Clin Exp Dermatol

Publisher Oxford University Press

Specialty Dermatology

Date 1999 Dec 22

PMID 10606946

Citations 11

Authors

W M Porter

C M Hardman

S H Abdalla

A V Powles

Affiliations

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Abstract

We report two siblings with Rothmund-Thomson syndrome (RTS); the older sister died of acute myeloblastic leukaemia and the younger sister has a slowly progressive leucopenia. Her prognosis is guarded in view of the increased incidence of neoplasms in this condition. More than 200 cases of RTS have now been reported worldwide.1 This is the first report of siblings with haematological disease and RTS.

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