Methylsulfomycin I, a New Cyclic Peptide Antibiotic from a Streptomyces Sp. HIL Y-9420704

Overview

Journal J Nat Prod

Date 1999 Dec 2

PMID 10579874

Citations 8

Authors

E K Vijaya Kumar

J Kenia

T Mukhopadhyay

S R Nadkarni

Affiliations

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Abstract

Methylsulfomycin I (1) is a new cyclic peptide antibiotic isolated from the fermentation broth of a Streptomyces sp. HIL Y-9420704. Its structure was elucidated by NMR and GC-MS. The in vitro activity (MIC) against a wide range of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-, and teicoplanin-resistant strains, is described.

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